The soluble type of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL by way of direct protein–protein interplay in glioblastoma
Background: Focused approaches for inhibiting epidermal progress issue receptor (EGFR) and different receptor tyrosine kinases (RTKs) in glioblastoma (GBM) have led to therapeutic resistance and little scientific profit, elevating the necessity for the event of different methods.
Endogenous LRIG1 (Leucine-rich Repeats and ImmunoGlobulin-like domains protein 1) is an RTK inhibitory protein required for stem cell upkeep, and we beforehand demonstrated the soluble ectodomain of LRIG1 (sLRIG1) to potently inhibit GBM progress in vitro and in vivo.
Anti-Retinoblastoma binding protein 6 (5A11)
Strategies: Right here, we generated a recombinant protein of the ectodomain of LRIG1 (sLRIG1) and decided its exercise in numerous mobile GBM fashions together with patient-derived stem-like cells and affected person organoids. We used proliferation, adhesion, and invasion assays, and carried out gene and protein expression research. Proximity ligation assay and NanoBiT complementation expertise have been utilized to evaluate protein-protein interactions.
Outcomes:We present that recombinant sLRIG1 downregulates EGFRvIII however not EGFR, and reduces proliferation in GBM cells, regardless of their EGFR expression standing. We discover that sLRIG1 targets and downregulates a variety of RTKs, together with AXL, and alters GBM cell adhesion. Mechanistically, we show that LRIG1 interferes with AXL however not with EGFR dimerization.
Conclusions: These outcomes establish AXL as a novel sLRIG1 goal and present that LRIG1-mediated RTK downregulation relies on direct protein interplay. The pan-RTK inhibitory exercise of sLRIG1 warrants additional investigation for brand new GBM remedy approaches.
RBBP4 Retinoblastoma Binding Protein four Human Recombinant Protein
Key phrases: AXL; EGFR; LRIG1; glioblastoma; receptor tyrosine kinase.
Recombinant Human Retinoblastoma Binding Protein 9 |
MBS145284-0005mg |
MyBiosource |
0.005mg |
EUR 240 |
Recombinant Human Retinoblastoma Binding Protein 9 |
MBS145284-002mg |
MyBiosource |
0.02mg |
EUR 310 |
Recombinant Human Retinoblastoma Binding Protein 9 |
MBS145284-1mg |
MyBiosource |
1mg |
EUR 2880 |
Recombinant Human Retinoblastoma Binding Protein 9 |
MBS145284-5x1mg |
MyBiosource |
5x1mg |
EUR 12630 |
Retinoblastoma Binding Protein 4 Human Recombinant |
rAP-4659 |
Angio Proteomie |
Inquiry |
Ask for price |
Retinoblastoma Binding Protein 9 Human Recombinant |
rAP-4661 |
Angio Proteomie |
Inquiry |
Ask for price |
Rabbit anti-human retinoblastoma binding protein 7 polyclonal Antibody |
MBS713630-01mL |
MyBiosource |
0.1mL |
EUR 485 |
Rabbit anti-human retinoblastoma binding protein 7 polyclonal Antibody |
MBS713630-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2175 |
Human Retinoblastoma- binding protein 5, RBBP5 ELISA KIT |
ELI-35542h |
Nova Lifetech |
96tests |
EUR 696 |
Retinoblastoma Binding Protein 9 Protein |
20-abx261527 |
Abbexa |
-
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Retinoblastoma Binding Protein 4 Protein |
20-abx260923 |
Abbexa |
-
Ask for price
-
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-
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Retinoblastoma Binding Protein 9 Protein |
abx261527-100g |
Abbexa |
100 µg |
EUR 3550 |
Retinoblastoma Binding Protein 9 Protein |
abx261527-10g |
Abbexa |
10 µg |
EUR 325 |
Retinoblastoma Binding Protein 9 Protein |
abx261527-2g |
Abbexa |
2 µg |
EUR 225 |
Retinoblastoma Binding Protein 4 Protein |
abx260923-10g |
Abbexa |
10 µg |
EUR 325 |
Retinoblastoma Binding Protein 4 Protein |
abx260923-2g |
Abbexa |
2 µg |
EUR 225 |
RBBP9 Retinoblastoma Binding Protein 9 Human Recombinant Protein |
PROTO75884 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
Description: RBBP9 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 206 amino acids (1-186 a.a.) and having a molecular mass of 23.1kDa.;RBBP9 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
RBBP4 Retinoblastoma Binding Protein 4 Human Recombinant Protein |
PROTQ09028 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
Description: RBBP4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 449 amino acids (1-425 a.a) and having a molecular mass of 50.2kDa.;RBBP4 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Retinoblastoma Binding Protein 4 (RBBP4) Antibody |
20-abx115147 |
Abbexa |
-
Ask for price
-
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Retinoblastoma Binding Protein 5 (RBBP5) Antibody |
20-abx115148 |
Abbexa |
-
Ask for price
-
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Retinoblastoma Binding Protein 6 (RBBP6) Antibody |
20-abx115149 |
Abbexa |
-
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-
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Retinoblastoma Binding Protein 8 (RBBP8) Antibody |
20-abx115151 |
Abbexa |
-
Ask for price
-
Ask for price
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Retinoblastoma Binding Protein 9 (RBBP9) Antibody |
20-abx115152 |
Abbexa |
-
Ask for price
-
Ask for price
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Retinoblastoma Binding Protein 4 (RBBP4) Antibody |
abx115147-100l |
Abbexa |
100 µl |
EUR 612.5 |
Retinoblastoma Binding Protein 5 (RBBP5) Antibody |
abx115148-100l |
Abbexa |
100 µl |
EUR 612.5 |
Retinoblastoma Binding Protein 6 (RBBP6) Antibody |
abx115149-100l |
Abbexa |
100 µl |
EUR 612.5 |
Retinoblastoma Binding Protein 8 (RBBP8) Antibody |
abx115151-100l |
Abbexa |
100 µl |
EUR 612.5 |
Retinoblastoma Binding Protein 9 (RBBP9) Antibody |
abx115152-100l |
Abbexa |
100 µl |
EUR 612.5 |
RBBP7 (untagged)-Human retinoblastoma binding protein 7 (RBBP7), transcript variant 2 |
SC118334 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Rabbit anti-human retinoblastoma binding protein 5 polyclonal Antibody |
MBS714819-01mL |
MyBiosource |
0.1mL |
EUR 485 |
Rabbit anti-human retinoblastoma binding protein 5 polyclonal Antibody |
MBS714819-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2175 |
Rabbit anti-human retinoblastoma binding protein 6 polyclonal Antibody |
MBS714443-01mL |
MyBiosource |
0.1mL |
EUR 485 |
Rabbit anti-human retinoblastoma binding protein 6 polyclonal Antibody |
MBS714443-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2175 |
Rabbit anti-human retinoblastoma binding protein 8 polyclonal Antibody |
MBS716279-01mL |
MyBiosource |
0.1mL |
EUR 485 |
Rabbit anti-human retinoblastoma binding protein 8 polyclonal Antibody |
MBS716279-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2175 |
Rabbit anti-human retinoblastoma binding protein 9 polyclonal Antibody |
MBS711597-01mL |
MyBiosource |
0.1mL |
EUR 485 |
Rabbit anti-human retinoblastoma binding protein 9 polyclonal Antibody |
MBS711597-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2175 |
Rabbit anti-human retinoblastoma binding protein 4 polyclonal Antibody |
MBS711397-01mL |
MyBiosource |
0.1mL |
EUR 485 |
Rabbit anti-human retinoblastoma binding protein 4 polyclonal Antibody |
MBS711397-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2175 |
RbBP5 (Retinoblastoma Binding Protein 5, RbBP-5, RBQ3, Retinoblastoma Binding Protein RBQ3, SWD1, SWD1 Set1c WD40 Repeat Protein Homolog) |
MBS619518-01mg |
MyBiosource |
0.1mg |
EUR 550 |
RbBP5 (Retinoblastoma Binding Protein 5, RbBP-5, RBQ3, Retinoblastoma Binding Protein RBQ3, SWD1, SWD1 Set1c WD40 Repeat Protein Homolog) |
MBS619518-5x01mg |
MyBiosource |
5x0.1mg |
EUR 2330 |
RBBP7 (GFP-tagged) - Human retinoblastoma binding protein 7 (RBBP7), transcript variant 1 |
RG231256 |
Origene Technologies GmbH |
10 µg |
Ask for price |
RBBP7 (GFP-tagged) - Human retinoblastoma binding protein 7 (RBBP7), transcript variant 2 |
RG217969 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Retinoblastoma binding protein 1 (ARID4A) (NM_002892) Human Over-expression Lysate |
LS005926 |
BosterBio |
100ug |
EUR 960 |
|
Description: Transient overexpression lysate of AT rich interactive domain 4A (RBP1-like) (ARID4A), transcript variant 1 |
Lenti ORF clone of Human retinoblastoma binding protein 9 (RBBP9), mGFP tagged |
RC202090L2 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Lenti ORF clone of Human retinoblastoma binding protein 9 (RBBP9), mGFP tagged |
RC202090L4 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Rbbp7 (untagged ORF) - Rat retinoblastoma binding protein 7 (Rbbp7), (10 ug) |
RN209545 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Rbbp7 (Myc-DDK-tagged) - Mouse retinoblastoma binding protein 7 (Rbbp7) |
MR206775 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Jumonji/ARID Domain Containing Protein 1A (JARID1A, KDM5A, Retinoblastoma Binding Protein 2, RBBP2, RBP2, Retinoblastoma Binding Protein 2 Homolog, RBP2-H1) |
MBS614628-01mL |
MyBiosource |
0.1mL |
EUR 905 |
Jumonji/ARID Domain Containing Protein 1A (JARID1A, KDM5A, Retinoblastoma Binding Protein 2, RBBP2, RBP2, Retinoblastoma Binding Protein 2 Homolog, RBP2-H1) |
MBS614628-5x01mL |
MyBiosource |
5x0.1mL |
EUR 3925 |
RBBP7 (Myc-DDK-tagged)-Human retinoblastoma binding protein 7 (RBBP7), transcript variant 2 |
RC217969 |
Origene Technologies GmbH |
10 µg |
Ask for price |
Thioredoxin interacting protein (TXNIP) acts as a tumor suppressor in human prostate most cancers
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Nonetheless, the expression degree and organic capabilities of TXNIP in PCa haven’t been recognized but. Due to this fact, this examine goals to research the expression and organic capabilities of TXNIP in PCa. We reported that the expression of TXNIP was considerably decreased in PCa and related to clinicopathological options.
Pig Retinoblastoma tumor suppressor protein ELISA package
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Overexpression of TXNIP might considerably inhibited PC-Three cells proliferation, migration, invasion, and glucose uptake. Moreover, overexpression of TXNIP could remarkably block cell cycle in the G0/G1 section and promenadeoted cell apoptosis. Moreover, TXNIP expression correlated inversely with GLUT1 expression in PCa.
Pig Retinoblastoma tumor suppressor protein ELISA kit |
E07P0713-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Retinoblastoma tumor suppressor protein ELISA kit |
E07P0713-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Retinoblastoma tumor suppressor protein ELISA kit |
E08P0713-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Canine Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Retinoblastoma tumor suppressor protein ELISA kit |
E08P0713-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Canine Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Retinoblastoma tumor suppressor protein ELISA kit |
E08P0713-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Canine Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Retinoblastoma tumor suppressor protein ELISA kit |
E01A15860 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Rat Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS012372-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Rat Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS012372-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Rat Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS012372-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Rat Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS012372-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Cat Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS084880-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Rat Retinoblastoma tumor suppressor protein ELISA Kit |
MBS728541-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Rat Retinoblastoma tumor suppressor protein ELISA Kit |
MBS728541-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Rat Retinoblastoma tumor suppressor protein ELISA Kit |
MBS728541-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Rat Retinoblastoma tumor suppressor protein ELISA Kit |
MBS728541-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Goat Retinoblastoma tumor suppressor protein ELISA kit |
E01A50763 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Goat Retinoblastoma tumor suppressor protein ELISA kit |
E06P0713-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Goat Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Retinoblastoma tumor suppressor protein ELISA kit |
E06P0713-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Goat Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Retinoblastoma tumor suppressor protein ELISA kit |
E06P0713-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Goat Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Duck Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS096163-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Fish Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS006300-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Goat Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS032012-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Cavy Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS041490-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Goat Retinoblastoma tumor suppressor protein ELISA Kit |
MBS746721-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Goat Retinoblastoma tumor suppressor protein ELISA Kit |
MBS746721-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Goat Retinoblastoma tumor suppressor protein ELISA Kit |
MBS746721-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Goat Retinoblastoma tumor suppressor protein ELISA Kit |
MBS746721-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Human Retinoblastoma tumor suppressor protein ELISA kit |
E01A7114 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Mouse Retinoblastoma tumor suppressor protein ELISA kit |
E01A24607 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Sheep Retinoblastoma tumor suppressor protein ELISA kit |
E01A103057 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Human Retinoblastoma tumor suppressor protein ELISA kit |
E01P0713-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Human Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Retinoblastoma tumor suppressor protein ELISA kit |
E01P0713-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Human Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Retinoblastoma tumor suppressor protein ELISA kit |
E01P0713-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Human Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Retinoblastoma tumor suppressor protein ELISA kit |
E03P0713-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Retinoblastoma tumor suppressor protein ELISA kit |
E03P0713-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Retinoblastoma tumor suppressor protein ELISA kit |
E03P0713-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Camel Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS095853-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Camel Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS095853-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Camel Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS095853-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Camel Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS095853-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Goose Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS023499-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Mouse Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS031618-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Mouse Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS031618-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Mouse Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS031618-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Mouse Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS031618-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Human Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS045300-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Human Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS045300-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Human Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS045300-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Human Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS045300-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Horse Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS037832-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Horse Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS037832-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Horse Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS037832-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Horse Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS037832-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Sheep Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS037863-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Sheep Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS037863-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Sheep Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS037863-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Sheep Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS037863-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Human Retinoblastoma tumor suppressor protein ELISA Kit |
MBS721558-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Human Retinoblastoma tumor suppressor protein ELISA Kit |
MBS721558-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Human Retinoblastoma tumor suppressor protein ELISA Kit |
MBS721558-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Human Retinoblastoma tumor suppressor protein ELISA Kit |
MBS721558-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Mouse Retinoblastoma tumor suppressor protein ELISA Kit |
MBS729868-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Mouse Retinoblastoma tumor suppressor protein ELISA Kit |
MBS729868-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Mouse Retinoblastoma tumor suppressor protein ELISA Kit |
MBS729868-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Mouse Retinoblastoma tumor suppressor protein ELISA Kit |
MBS729868-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Sheep Retinoblastoma tumor suppressor protein ELISA Kit |
MBS744766-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Sheep Retinoblastoma tumor suppressor protein ELISA Kit |
MBS744766-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Sheep Retinoblastoma tumor suppressor protein ELISA Kit |
MBS744766-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Sheep Retinoblastoma tumor suppressor protein ELISA Kit |
MBS744766-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Rabbit Retinoblastoma tumor suppressor protein ELISA kit |
E01A33329 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Canine Retinoblastoma tumor suppressor protein ELISA kit |
E01A68192 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Bovine Retinoblastoma tumor suppressor protein ELISA kit |
E01A85630 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Rabbit Retinoblastoma tumor suppressor protein ELISA kit |
E04P0713-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Retinoblastoma tumor suppressor protein ELISA kit |
E04P0713-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Retinoblastoma tumor suppressor protein ELISA kit |
E04P0713-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Retinoblastoma tumor suppressor protein ELISA kit |
E01A76910 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Monkey Retinoblastoma tumor suppressor protein ELISA kit |
E09P0713-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Retinoblastoma tumor suppressor protein ELISA kit |
E09P0713-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Retinoblastoma tumor suppressor protein ELISA kit |
E09P0713-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Retinoblastoma tumor suppressor protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Donkey Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS097226-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Canine Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS022327-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS022327-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS022327-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS022327-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Bovine Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS022890-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Bovine Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS022890-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Bovine Retinoblastoma Tumor Suppressor Protein ELISA Kit |
MBS022890-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
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Taken collectively, our outcomes for the primary time revealed that TXNIP was decreased in PCa. Furthermore, TXNIP may act as a tumor suppressor of PCa and correlated with tumor prevalence and improvement. Our findings solid a brand new ligh
t on higher understanding the prevalence and improvement of PCa and indicated that TXNIP is likely to be favorable for PCa molecular goal remedy.
Key phrases: PC-Three cells; glucose transporter 1; proliferation; prostate most cancers; thioredoxin interacting protein; tumor suppressor.
Human retinoblastoma tumor suppressor protein(pRB)ELISA Package
- Is the largest menace to human being globally. The primary case was recognized in a affected person with flu signs together with extreme acute respiratory syndrome in Wuhan, China in December 2019 and now it has unfold in additional than 200 nations. Is extra deadly within the aged and folks with an underlying situation resembling bronchial asthma, most cancers, diabetes.
- Right here we carried out bioinformatic evaluation to research the interplay of S2 subunit protein of SARS-nCoV-2 of novel coronavirus with tumor suppressor proteins p53 and BRCA-1\/2. On this short communication we report the interaction between S2 subunit proteins with tumor suppressor proteins for the primary time. This preliminary end result will open up a brand new route to research the impact of a novel coronavirus in most cancers sufferers.