Evaluation of the expression and affiliation of retinoblastoma binding protein 6 (RBBP6) with the JNK signaling pathway in prostate cancers
This research goals to research the expression of retinoblastoma binding protein 6 (RBBP6) in prostate most cancers (PCa) and its affiliation with the c-Jun N-terminal kinase (JNK) pathway.
Immunohistochemistry was used to detect RBBP6 and JNK1/2 expression in PCa and benign prostatic hyperplasia (BPH) tissues.
RBBP6 expression in PCa cells (LNCap, PC3 and DU145) and noncancerous prostate epithelial cells (RWPE-1) was decided by qRT-PCR and Western blotting. PC3 and DU145 cells had been transfected with RBBP6 siRNAs to look at the organic traits. Anisomycin (a JNK activator) with/with out RBBP6 siRNA was used to deal with PC3 cells for additional investigating the ramification of the RBBP6-mediated JNK pathway in PCa. PCa tissues and cells confirmed larger RBBP6 and JNK1/2 expression.
Recombinant Retinoblastoma Protein 1 (RB1)
RBBP6 was positively correlated with JNK1/2 in PCa tissues. Apart from, RBBP6 expression was correlated to scientific tumor stage, lymph node metastasis, Gleason grade, preoperative PSA degree, in addition to prognosis of PCa. RBBP6 siRNA lowered cell proliferation, arrested cells at G2/M, and promoted cell apoptosis, and suppressed JNK pathway.
Moreover, migration and invasion decreased after the RBBP6 siRNA transfection with downregulated MMP-2 and MMP-9. Anisomycin promoted the proliferation, invasion and migration of PC3 cells and inhibited PC3 cell apoptosis, which could possibly be reversed by RBBP6 siRNA. RBBP6 expression was upregulated in PCa tissues and positively correlated with expression degree of JNK1/2.
With inhibition of RBBP6 expression, the proliferation, invasion and migration of PCa cells decreased dramatically, whereas PC3 cell apoptosis elevated appreciably, accompanied by suppression of the JNK pathway. This text is protected by copyright. All rights reserved.
Retinoblastoma Protein 1 Phospho-Thr826 (RB1 pT826) Antibody
Key phrases: Apoptosis; Most cancers; Cell migration; Gene remedy.
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx037361-100ug | Abbexa | 100 ug | EUR 391 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx011911-100ul | Abbexa | 100 ul | EUR 411 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx008782 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx001728 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx032759-400ul | Abbexa | 400 ul | EUR 523 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx032759-80l | Abbexa | 80 µl | EUR 286 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx034004-400ul | Abbexa | 400 ul | EUR 523 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx034004-80l | Abbexa | 80 µl | EUR 286 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx320518 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx237141-100ug | Abbexa | 100 ug | EUR 509 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx237142-100ug | Abbexa | 100 ug | EUR 551 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx214314 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx141027 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx141070 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx141167 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx329342 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx329620 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx331681-100ul | Abbexa | 100 ul | EUR 425 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx332050-100ul | Abbexa | 100 ul | EUR 425 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx332098-100ul | Abbexa | 100 ul | EUR 425 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx332214-100ul | Abbexa | 100 ul | EUR 425 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx326789 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx326790 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx326791 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx328550 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx328752 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Protein |
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20-abx260454 | Abbexa |
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![]() Recombinant Retinoblastoma Protein 1 (RB1) |
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4-RPB211Hu01 | Cloud-Clone |
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Description: Recombinant Human Retinoblastoma Protein 1 expressed in: E.coli |
![]() Recombinant Retinoblastoma Protein 1 (RB1) |
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4-RPB211Hu02 | Cloud-Clone |
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Description: Recombinant Human Retinoblastoma Protein 1 expressed in: E.coli |
![]() Retinoblastoma Protein 1 (Rb1) Antibody Pair |
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abx117561-1pair5x96wellplates | Abbexa | 1 pair (5x96 well plates) | EUR 1010 |
![]() Retinoblastoma Protein 1 (RB1) Antibody (Biotin) |
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20-abx272104 | Abbexa |
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![]() Human Retinoblastoma Protein 1 (RB1) Protein |
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20-abx068874 | Abbexa |
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![]() Human Retinoblastoma Protein 1 (RB1) Protein |
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20-abx068875 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human) |
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4-PAB211Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1) |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human) |
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4-PAB211Hu02 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1) |
![]() Rat Retinoblastoma-associated protein (Rb1) |
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1-CSB-RP155294r(A3) | Cusabio |
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Description: Recombinant Rat Retinoblastoma-associated protein(Rb1),partial expressed in E.coli |
![]() Human Retinoblastoma Protein 1 (RB1) ELISA Kit |
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SEB211Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 4502.43 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Retinoblastoma Protein 1 (RB1) in Tissue homogenates, cell lysates and other biological fluids. |
![]() Human Retinoblastoma Protein 1 (RB1) ELISA Kit |
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SEB211Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 458.44 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Retinoblastoma Protein 1 (RB1) in Tissue homogenates, cell lysates and other biological fluids. |
![]() Human Retinoblastoma Protein 1 (RB1) ELISA Kit |
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SEB211Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 612.05 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Retinoblastoma Protein 1 (RB1) in Tissue homogenates, cell lysates and other biological fluids. |
![]() Human Retinoblastoma Protein 1 (RB1) ELISA Kit |
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SEB211Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 2454.23 |
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Retinoblastoma Protein 1 (RB1) in Tissue homogenates, cell lysates and other biological fluids. |
![]() Human Retinoblastoma Protein 1 (RB1) ELISA Kit |
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4-SEB211Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Retinoblastoma Protein 1 (RB1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
![]() Human Retinoblastoma Protein 1 (RB1) ELISA Kit |
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20-abx152929 | Abbexa |
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![]() Human Retinoblastoma Protein 1 (RB1) CLIA Kit |
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20-abx492490 | Abbexa |
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![]() Human Retinoblastoma Protein 1 (RB1) ELISA Kit |
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abx253095-96tests | Abbexa | 96 tests | EUR 707 |
![]() Pig Retinoblastoma Protein 1 (RB1) ELISA Kit |
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abx360817-96tests | Abbexa | 96 tests | EUR 825 |
![]() Rabbit Retinoblastoma Protein 1 (RB1) ELISA Kit |
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abx363643-96tests | Abbexa | 96 tests | EUR 825 |
![]() Sheep Retinoblastoma Protein 1 (RB1) ELISA Kit |
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abx364326-96tests | Abbexa | 96 tests | EUR 926 |
![]() Chicken Retinoblastoma Protein 1 (RB1) ELISA Kit |
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abx355616-96tests | Abbexa | 96 tests | EUR 825 |
![]() Monkey Retinoblastoma Protein 1 (RB1) ELISA Kit |
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abx358739-96tests | Abbexa | 96 tests | EUR 825 |
![]() Human RB1(Retinoblastoma Protein 1) ELISA Kit |
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EH3703 | FN Test | 96T | EUR 524.1 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
![]() Human Retinoblastoma Protein 1(RB1)ELISA Kit |
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QY-E01519 | Qayee Biotechnology | 96T | EUR 361 |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), APC |
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4-PAB211Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with APC. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), Biotinylated |
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4-PAB211Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with Biotin. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), Cy3 |
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4-PAB211Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with Cy3. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), FITC |
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4-PAB211Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with FITC. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), HRP |
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4-PAB211Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with HRP. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), PE |
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4-PAB211Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with PE. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), APC |
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4-PAB211Hu02-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with APC. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), Biotinylated |
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4-PAB211Hu02-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with Biotin. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), Cy3 |
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4-PAB211Hu02-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with Cy3. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), FITC |
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4-PAB211Hu02-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with FITC. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), HRP |
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4-PAB211Hu02-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with HRP. |
![]() Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), PE |
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4-PAB211Hu02-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with PE. |
![]() Retinoblastoma Protein 1 Phospho-Ser807 (RB1 pS807) Antibody |
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20-abx125454 | Abbexa |
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![]() Retinoblastoma Protein 1 Phospho-Ser612 (RB1 pS612) Antibody |
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20-abx323083 | Abbexa |
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![]() Retinoblastoma Protein 1 Phospho-Thr826 (RB1 pT826) Antibody |
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abx333137-100ul | Abbexa | 100 ul | EUR 467 |
![]() Retinoblastoma Protein 1 Phospho-Ser780 (RB1 pS780) Antibody |
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abx333182-100ul | Abbexa | 100 ul | EUR 467 |
![]() Retinoblastoma Protein 1 Phospho-Ser795 (RB1 pS795) Antibody |
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abx333183-100ul | Abbexa | 100 ul | EUR 467 |
Retinoblastoma protein expression and its predictors in triple-negative breast most cancers
- BACKGROUND Lengthy noncoding RNA (lncRNA) acts as key regulator in human cancers, together with retinoblastoma. Nonetheless, the perform of LINC00152 stays largely unknown in retinoblastoma.
Phospho- Retinoblastoma (Ser780) Antibody
Retinoblastoma (Phospho-Thr373) Antibody detects endogenous ranges of Retinoblastoma solely when phosphorylated at Thr373.
- Thus, this research aimed to discover the function and molecular mechanisms of LINC00152 in retinoblastoma. MATERIAL AND METHODS The true-time quantitative polymerase chain response (RT-qPCR) was used to quantify the expression ranges of LINC00152, miR-613 and yes-associated protein 1 (YAP1). The target genes of LINC00152 and miR-613 had been recognized by dual-luciferase reporter evaluation, RNA immunoprecipitation (RIP) and RNA pulldown assays.
- The viability, apoptosis, and invasion of retinoblastoma cells had been assessed by Cell Counting Package-8, move cytometry, and Transwell assays, respectively. As well as, western blot was used to check the protein expression in retinoblastoma cells or tissues. Cell sensitivity to carboplatin and adriamycin was analyzed by computing IC₅₀ worth.
![]() Retinoblastoma Antibody |
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AF6103 | Affbiotech | 200ul | EUR 304 |
Description: Retinoblastoma Antibody detects endogenous levels of total Retinoblastoma. |
![]() Retinoblastoma Antibody |
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ABF6103 | Lifescience Market | 100 ug | EUR 438 |
![]() Retinoblastoma Antibody |
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20-abx012903 | Abbexa |
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![]() Retinoblastoma antibody (Ser788) |
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70R-32616 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal Retinoblastoma antibody (Ser788) |
![]() Retinoblastoma antibody (Ser608) |
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70R-32617 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal Retinoblastoma antibody (Ser608) |
![]() Retinoblastoma antibody (Ser249) |
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70R-33653 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal Retinoblastoma antibody (Ser249) |
![]() Retinoblastoma antibody (Thr826) |
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70R-33655 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal Retinoblastoma antibody (Thr826) |
![]() Retinoblastoma 1 Antibody |
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20-abx115146 | Abbexa |
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![]() Retinoblastoma (pS780) Antibody |
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20-abx119318 | Abbexa |
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![]() Retinoblastoma (pS807) Antibody |
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20-abx119319 | Abbexa |
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![]() Retinoblastoma (pS612) Antibody |
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abx218208-100ug | Abbexa | 100 ug | EUR 439 |
![]() Retinoblastoma (pT252) Antibody |
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abx218209-100ug | Abbexa | 100 ug | EUR 439 |
![]() Retinoblastoma (pS788) Antibody |
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abx218210-100ug | Abbexa | 100 ug | EUR 439 |
![]() Retinoblastoma (pT373) Antibody |
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abx218211-100ug | Abbexa | 100 ug | EUR 439 |
![]() Retinoblastoma (pT826) Antibody |
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abx011460-100ug | Abbexa | 100 ug | EUR 439 |
![]() Retinoblastoma (pS780) Antibody |
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abx011461-100ug | Abbexa | 100 ug | EUR 439 |
![]() Retinoblastoma (pS795) Antibody |
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abx011462-100ug | Abbexa | 100 ug | EUR 439 |
![]() Retinoblastoma (pS807) Antibody |
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abx011463-100ug | Abbexa | 100 ug | EUR 439 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx126458 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx121694 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx123188 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx320518 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx237141-100ug | Abbexa | 100 ug | EUR 509 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx237142-100ug | Abbexa | 100 ug | EUR 551 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx214314 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx329342 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx329620 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx331681-100ul | Abbexa | 100 ul | EUR 425 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx332050-100ul | Abbexa | 100 ul | EUR 425 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx332098-100ul | Abbexa | 100 ul | EUR 425 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx332214-100ul | Abbexa | 100 ul | EUR 425 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
20-abx326789 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx326790 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx326791 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx328550 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx328752 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx001728 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx102399 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx102401 | Abbexa |
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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abx037361-100ug | Abbexa | 100 ug | EUR 391 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx141167 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx141027 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx141070 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx136094 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
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20-abx008782 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx011911-100ul | Abbexa | 100 ul | EUR 411 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx032759-400ul | Abbexa | 400 ul | EUR 523 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx032759-80l | Abbexa | 80 µl | EUR 286 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx034004-400ul | Abbexa | 400 ul | EUR 523 |
![]() Retinoblastoma Protein 1 (RB1) Antibody |
|||
abx034004-80l | Abbexa | 80 µl | EUR 286 |
![]() Retinoblastoma Protein 1 (RB1) Protein |
|||
20-abx260454 | Abbexa |
|
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![]() Retinoblastoma Binding Protein 4 Protein |
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20-abx260923 | Abbexa |
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![]() Retinoblastoma Binding Protein 9 Protein |
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20-abx261527 | Abbexa |
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![]() Retinoblastoma Binding Protein 4 (RBBP4) Antibody |
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20-abx115147 | Abbexa |
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![]() Retinoblastoma Binding Protein 5 (RBBP5) Antibody |
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20-abx115148 | Abbexa |
|
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![]() Retinoblastoma Binding Protein 6 (RBBP6) Antibody |
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20-abx115149 | Abbexa |
|
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![]() Retinoblastoma Binding Protein 7 (RBBP7) Antibody |
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20-abx115150 | Abbexa |
|
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![]() Retinoblastoma Binding Protein 8 (RBBP8) Antibody |
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20-abx115151 | Abbexa |
|
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![]() Retinoblastoma Binding Protein 9 (RBBP9) Antibody |
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20-abx115152 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (Rb1) Antibody Pair |
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abx117561-1pair5x96wellplates | Abbexa | 1 pair (5x96 well plates) | EUR 1010 |
![]() Retinoblastoma-Like Protein 1 (RBL1) Antibody |
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20-abx317949 | Abbexa |
|
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![]() Retinoblastoma Protein 1 (RB1) Antibody (Biotin) |
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20-abx272104 | Abbexa |
|
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![]() Retinoblastoma-Like Protein 2 (RBL2) Antibody |
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abx224096-100ug | Abbexa | 100 ug | EUR 411 |
![]() Retinoblastoma-like protein 1 (RBL1) Antibody |
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20-abx325137 | Abbexa |
|
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![]() Retinoblastoma-Like Protein 1 (RBL1) Antibody |
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abx030987-400ul | Abbexa | 400 ul | EUR 523 |
![]() Retinoblastoma-Like Protein 1 (RBL1) Antibody |
|||
abx030987-80l | Abbexa | 80 µl | EUR 286 |
![]() Phospho-Retinoblastoma(Thr826) Antibody |
|||
AF0030 | Affbiotech | 200ul | EUR 304 |
Description: Phospho-Retinoblastoma(Thr826) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Threonine 826. |
![]() Phospho-Retinoblastoma (Ser780) Antibody |
|||
AF3103 | Affbiotech | 200ul | EUR 304 |
Description: Phospho-Retinoblastoma (Ser780) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Serine 780. |
![]() Phospho-Retinoblastoma (Ser795) Antibody |
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AF3104 | Affbiotech | 200ul | EUR 304 |
Description: Phospho-Retinoblastoma (Ser795) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Serine 795. |
![]() Phospho-Retinoblastoma (Ser807) Antibody |
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AF3105 | Affbiotech | 200ul | EUR 304 |
Description: Phospho-Retinoblastoma (Ser807) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Serine 807. |
![]() Phospho-Retinoblastoma (Ser612) Antibody |
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AF8057 | Affbiotech | 200ul | EUR 376 |
Description: Retinoblastoma (Phospho-Ser612) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Ser612. |
![]() Phospho-Retinoblastoma (Thr252) Antibody |
|||
AF8124 | Affbiotech | 200ul | EUR 376 |
Description: Retinoblastoma (Phospho-Thr252) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Thr252. |
![]() Phospho-Retinoblastoma (Ser788) Antibody |
|||
AF8125 | Affbiotech | 200ul | EUR 376 |
Description: Retinoblastoma (Phospho-Ser788) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Ser788. |
![]() Phospho-Retinoblastoma (Thr373) Antibody |
|||
AF8399 | Affbiotech | 200ul | EUR 376 |
Description: Retinoblastoma (Phospho-Thr373) Antibody detects endogenous levels of Retinoblastoma only when phosphorylated at Thr373. |
![]() Retinoblastoma (Phospho- Ser612) Antibody |
|||
ABF8057 | Lifescience Market | 100 ug | EUR 438 |
![]() Retinoblastoma (Phospho- Thr252) Antibody |
|||
ABF8124 | Lifescience Market | 100 ug | EUR 438 |
![]() Retinoblastoma (Phospho- Ser788) Antibody |
|||
ABF8125 | Lifescience Market | 100 ug | EUR 438 |
![]() Retinoblastoma (Phospho- Thr373) Antibody |
|||
ABF8399 | Lifescience Market | 100 ug | EUR 438 |
![]() Phospho- Retinoblastoma (Thr826) Antibody |
|||
ABF0030 | Lifescience Market | 100 ug | EUR 438 |
![]() Phospho- Retinoblastoma (Ser780) Antibody |
|||
ABF3103 | Lifescience Market | 100 ug | EUR 438 |
![]() Phospho- Retinoblastoma (Ser795) Antibody |
|||
ABF3104 | Lifescience Market | 100 ug | EUR 438 |
![]() Phospho- Retinoblastoma (Ser807) Antibody |
|||
ABF3105 | Lifescience Market | 100 ug | EUR 438 |
![]() Retinoblastoma recombinant monoclonal antibody |
|||
A5073 | Bimake | 100ul X 3 | EUR 595 |
Description: A recombinant monoclonal antibody from rabbit against human Retinoblastoma for WB, IF,ELISA |
![]() Phospho-Retinoblastoma (Thr826) Antibody |
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A1733-100 | Biovision | EUR 479 |
![]() Retinoblastoma (Phospho-Ser608) Antibody |
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20-abx012584 | Abbexa |
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![]() Retinoblastoma (Phospho-Ser608) Antibody |
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11720-100ul | SAB | 100ul | EUR 252 |
![]() Retinoblastoma (Phospho-Ser608) Antibody |
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11720-50ul | SAB | 50ul | EUR 187 |
![]() Retinoblastoma (Phospho-Thr826) Antibody |
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12106-100ul | SAB | 100ul | EUR 252 |
- The consequences of LINC00152 silencing in vivo had been measured by a xenograft experiment. RESULTS LINC00152 was clearly upregulated, whereas miR-613 was decreased in retinoblastoma tissues and cells. MiR-613, a goal of LINC00152, was negatively regulated by LINC00152. Purposeful experiment additional illustrated that silencing of LINC00152 evidently repressed proliferation, invasion, and autophagy whereas strengthened apoptosis of retinoblastoma cells, moreover, retinoblastoma cells had been extra delicate to carboplatin and adriamycin after knockdown of LINC00152.
Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human)
- Importantly, knockdown of LINC00152-induced results on retinoblastoma cells could possibly be overturned by introducing miR-613 inhibitor. Downregulation of miR-613 abolished silencing of YAP1-effects on proliferation, apoptosis, invasion, autophagy, and chemoresistance of retinoblastoma cells.
- The outcomes of the xenograft experiment indicated that LINC00152 silencing impeded tumor development in vivo. CONCLUSIONS Mechanistically, LINC00152 enhanced the aggressiveness of retinoblastoma and boosted carboplatin and adriamycin resistance by regulating YAP1 by sponging miR-613 in human retinoblastoma.