Recombinant Protein leading To Cardiac Pressure

rbprotein

 

Glycolaldehyde-Modified proteins trigger adversarial practical and structural aortic reworking resulting in cardiac strain overload

Rising proof helps the position of superior glycation finish merchandise (AGEs) within the growth of diabetic vascular problems and cardiovascular illnesses (CVDs). We now have proven that high-molecular-weight AGEs (HMW-AGEs), current in our Western eating regimen, impair cardiac perform. Whether or not HMW-AGEs have an effect on vascular perform stays unknown.

On this research, we aimed to research the affect of continual HMW-AGEs publicity on vascular perform and construction. Grownup male Sprague Dawley rats had been each day injected with HMW-AGEs or management resolution for six weeks. HMW-AGEs animals confirmed intracardiac strain overload, characterised by elevated systolic and imply pressures.

The contraction response to PE was elevated in aortic rings from the HMW-AGEs group. Leisure in response to ACh, however not SNP, was impaired by HMW-AGEs. This was related to decreased plasma cyclic GMP ranges. SOD restored ACh-induced leisure of HMW-AGEs animals to manage ranges, accompanied by a decreased half-maximal efficient dose (EC50).

 

rbprotein
rbprotein

Lastly, collagen deposition and intima-media thickness of the aortic vessel wall had been elevated with HMW-AGEs. Our knowledge show that continual HMW-AGEs publicity causes adversarial vascular remodelling. That is characterised by disturbed vasomotor perform attributable to elevated oxidative stress and structural modifications within the aorta, suggesting an vital contribution of HMW-AGEs within the growth of CVDs.

 

PRDM1 Recombinant Protein (Human)

Giant-scale, unbiased proteomics research are constrained by the complexity of the plasma proteome. Right here we report a extremely parallel protein quantitation platform integrating nanoparticle (NP) protein coronas with liquid chromatography-mass spectrometry for environment friendly proteomic profiling. A protein corona is a protein layer adsorbed onto NPs upon contact with biofluids.

Various the physicochemical properties of engineered NPs interprets to distinct protein corona patterns enabling differential and reproducible interrogation of organic samples, together with deep sampling of the plasma proteome. Spike experiments verify a linear sign response.

The median coefficient of variation was 22%. We screened 43 NPs and chosen a panel of 5, which detect greater than 2,000 proteins from 141 plasma samples utilizing a 96-well automated workflow in a pilot non-small cell lung most cancers classification research.

Our streamlined workflow combines depth of protection and throughput with exact quantification based mostly on distinctive interactions between proteins and NPs engineered for deep and scalable quantitative proteomic research.

 

Polyclonal BLIMP1 / PRDM1 Antibody (Inside)

Description: A polyclonal antibody raised in Goat that acknowledges and binds to Human BLIMP1 / PRDM1 (Inside). This antibody is examined and confirmed to work within the following purposes:

 

 

    • Bcl-2 inhibitors show an efficient exercise in acute myeloid leukemia (AML), however its scientific efficacy as a monotherapy was restricted partially owing to failure to focus on different antiapoptotic Bcl-2 household proteins, akin to Mcl-1.

 

    • On this context, the mixture technique could also be a promising strategy to beat this barrier. Right here, we report the preclinical efficacy of a novel technique combining ABT-199 with triptolide (TPL), a pure product extracted from a standard Chinese language medication, in AML.

 

    • Mixture therapy exhibited markedly elevated cytotoxicity in leukemic cells regardless of p53 standing whereas largely sparing regular cells of the hematopoietic lineage. Furthermore, co-administration of ABT-199 with TPL dramatically suppressed leukemia development in addition to extended animal survival in a xenograft AML mannequin.

 

    • The potentiated impact of ABT-199 and TPL towards AML was related to activation of the mitochondrum-related intrinsic apoptotic pathway by a mechanism reciprocally modulating Bcl-2 household proteins. On this case, TPL not solely downregulated Mcl-1 but additionally upregulated proapoptotic BH3-only proteins, thereby overcoming the resistance towards ABT-199.

 

    • Conversely, ABT-199 abrogated Bcl-2-mediated cytoprotection towards TPL. Collectively, these findings recommend that the routine combining TPL and ABT-199 may be energetic towards AML by inducing sturdy apoptosis by reciprocal regulation of anti- and proapoptotic Bcl-2 household proteins, due to this fact offering a powerful rationale for the scientific investigation of this mixture routine for the therapy of AML.

 

 

PRDM1 siRNA

20-abx929666
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

PRDM1 Peptide

42-727P 0.1 mg
EUR 405.6
Description: (CT) PRDM1 / BLIMP1 peptide

PRDM1 Peptide

42-784P 0.1 mg
EUR 405.6
Description: (IN) PRDM1 / MEL1 peptide

PRDM1 antibody

10R-2174 100 ul
EUR 483.6
Description: Mouse monoclonal PRDM1 antibody

PRDM1 Antibody

BF0254 200ul
EUR 540

PRDM1 Antibody

48403-100ul 100ul
EUR 399.6

PRDM1 Antibody

48403-50ul 50ul
EUR 286.8

PRDM1 Antibody

CSB-PA193485- each
EUR 402
Description: A polyclonal antibody against PRDM1. Recognizes PRDM1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

PRDM1 Antibody

CSB-PA193485-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against PRDM1. Recognizes PRDM1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

PRDM1 Antibody

R34682-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: PR domain containing 1, RP1-134E15.1, BLIMP1

PRDM1 Antibody

R33488-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: PR domain containing 1

PRDM1 Antibody

E10-30020 100μg/100μl
EUR 225
Description: Available in various conjugation types.

PRDM1 Antibody

E307250 100ug/200ul
EUR 275
Description: Available in various conjugation types.

PRDM1 Mouse mAb

E2220394 100ul
EUR 225
Description: Available in various conjugation types.

PRDM1 Rabbit pAb

A1960-100ul 100 ul
EUR 369.6

PRDM1 Rabbit pAb

A1960-200ul 200 ul
EUR 550.8

PRDM1 Rabbit pAb

A1960-20ul 20 ul
EUR 219.6

PRDM1 Rabbit pAb

A1960-50ul 50 ul
EUR 267.6

PRDM1 cloning plasmid

CSB-CL018638HU-10ug 10ug
EUR 568.8
Description: A cloning plasmid for the PRDM1 gene.

PRDM1 Antibody / BLIMP1

RQ4227 100 ug
EUR 356.15
Description: PR domain zinc finger protein 1, also known as B Lymphocyte Induced Maturation Protein 1 (BLIMP-1), is a protein that in humans is encoded by the PRDM1 gene. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

PRDM1 Blocking Peptide

BF0254-BP 1mg
EUR 234

PRDM1 Conjugated Antibody

C48403 100ul
EUR 476.4

PRDM1 Polyclonal Antibody

A-2001 100 µl Ask for price

PRDM1 Polyclonal Antibody

E91960 100ul
EUR 225
Description: Available in various conjugation types.

PRDM1 ELISA KIT|Human

EF005444 96 Tests
EUR 826.8

Human PRDM1 shRNA Plasmid

20-abx950435
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse PRDM1 shRNA Plasmid

20-abx969359
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

PRDM1 Recombinant Protein (Rat)

RP221939 100 ug Ask for price

PRDM1 Recombinant Protein (Mouse)

RP164228 100 ug Ask for price

PRDM1 Recombinant Protein (Human)

RP042457 100 ug Ask for price

Prdm1 ORF Vector (Rat) (pORF)

ORF073981 1.0 ug DNA
EUR 607.2

PRDM1 (N-term) Rabbit pAb

E2612764 100ul
EUR 225
Description: Available in various conjugation types.

PRDM1 ORF Vector (Human) (pORF)

ORF014153 1.0 ug DNA
EUR 424.8

Prdm1 ORF Vector (Mouse) (pORF)

ORF054744 1.0 ug DNA
EUR 607.2

Human PRDM1 Protein Lysate 20ug

IHUPRDM1PLLY20UG each
EUR 361
Description: Human PRDM1 Protein Lysate 20ug

Polyclonal PRDM1 Antibody (N-term)

APR03968G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PRDM1 (N-term). This antibody is tested and proven to work in the following applications:

Mouse Monoclonal Antibody to PRDM1

E10-30873 100ul
EUR 225
Description: Available in various conjugation types.

Mouse Monoclonal Antibody to PRDM1

E10-30874 100ul
EUR 225
Description: Available in various conjugation types.

Monoclonal PRDM1 Antibody, Clone: 5E7

AMM02750G 0.1ml
EUR 580.8
Description: A Monoclonal antibody against Human PRDM1. The antibodies are raised in Mouse and are from clone 5E7. This antibody is applicable in WB, E

Monoclonal PRDM1 Antibody, Clone: 2F1B6

AMM03067G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human PRDM1. The antibodies are raised in Mouse and are from clone 2F1B6. This antibody is applicable in WB and IHC, FC, ICC, E

Monoclonal PRDM1 Antibody, Clone: 7C11H1

AMM03066G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human PRDM1. The antibodies are raised in Mouse and are from clone 7C11H1. This antibody is applicable in WB and IHC, FC, ICC, E

PR/SET Domain 1 (PRDM1) Antibody

abx332134-100ul 100 ul
EUR 510

PR/SET Domain 1 (PRDM1) Antibody

abx016176-100ug 100 ug
EUR 493.2

PR/SET Domain 1 (PRDM1) Antibody

abx037111-100ug 100 ug
EUR 469.2

PR/SET Domain 1 (PRDM1) Antibody

abx028112-400ul 400 ul
EUR 627.6

PR/SET Domain 1 (PRDM1) Antibody

abx028112-80l 80 µl
EUR 343.2

PR/SET Domain 1 (PRDM1) Antibody

abx430328-200ul 200 ul
EUR 460.8

PR/SET Domain 1 (PRDM1) Antibody

abx430329-200ul 200 ul
EUR 460.8

PR/SET Domain 1 (PRDM1) Antibody

abx011375-100ul 100 ul
EUR 493.2

Polyclonal BLIMP1 / PRDM1 Antibody (Internal)

APG01185G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human BLIMP1 / PRDM1 (Internal). This antibody is tested and proven to work in the following applications:

Prdm1 sgRNA CRISPR Lentivector set (Rat)

K6508201 3 x 1.0 ug
EUR 406.8

PRDM1 sgRNA CRISPR Lentivector set (Human)

K1715601 3 x 1.0 ug
EUR 406.8

Prdm1 sgRNA CRISPR Lentivector set (Mouse)

K3985501 3 x 1.0 ug
EUR 406.8

Prdm1 3'UTR GFP Stable Cell Line

TU266727 1.0 ml Ask for price

Prdm1 3'UTR GFP Stable Cell Line

TU166893 1.0 ml Ask for price

PRDM1 3'UTR GFP Stable Cell Line

TU068764 1.0 ml
EUR 2799.6

Polyclonal PRDM1 / BLIMP1 Antibody (C-Term)

APG00388G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PRDM1 / BLIMP1 (C-Term). This antibody is tested and proven to work in the following applications:

PRDM1 Protein Vector (Rat) (pPM-C-HA)

PV295924 500 ng
EUR 1429.2

Polyclonal BLIMP1 / PRDM1 Antibody (C-Terminus)

APR02526G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BLIMP1 / PRDM1 (C-Terminus). This antibody is tested and proven to work in the following applications:

PRDM1 Protein Vector (Rat) (pPB-C-His)

PV295922 500 ng
EUR 1429.2

PRDM1 Protein Vector (Rat) (pPB-N-His)

PV295923 500 ng
EUR 1429.2

PRDM1 Protein Vector (Rat) (pPM-C-His)

PV295925 500 ng
EUR 1429.2

Polyclonal PRDM1 / MEL1 Antibody (internal region)

APG00624G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PRDM1 / MEL1 (internal region). This antibody is tested and proven to work in the following applications:

PRDM1 Protein Vector (Human) (pPM-C-HA)

PV056611 500 ng
EUR 577.2

PRDM1 Protein Vector (Mouse) (pPM-C-HA)

PV218976 500 ng
EUR 1278

PRDM1 Protein Vector (Human) (pPB-C-His)

PV056609 500 ng
EUR 577.2

PRDM1 Protein Vector (Human) (pPB-N-His)

PV056610 500 ng
EUR 577.2

PRDM1 Protein Vector (Human) (pPM-C-His)

PV056612 500 ng
EUR 577.2

PRDM1 Protein Vector (Mouse) (pPB-C-His)

PV218974 500 ng
EUR 1278

PRDM1 Protein Vector (Mouse) (pPB-N-His)

PV218975 500 ng
EUR 1278

PRDM1 Protein Vector (Mouse) (pPM-C-His)

PV218977 500 ng
EUR 1278

 

 

Monoclonal PRDM1 Antibody (monoclonal) (M01), Clone: 2B10

Description: A Monoclonal antibody towards Human PRDM1 (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2B10. This antibody is relevant in WB, E

Aptamer-directed Protein-specific A number of Modifications of Membrane Glycoproteins on Dwelling Cells

Understanding how a cell membrane protein capabilities on dwelling cells stays a problem for cell biology. Particular placement of practical molecules on particular proteins of their native atmosphere would enable complete research of proteins’ dynamic capabilities.

Present strategies can’t facilely obtain a number of modifications on particular membrane proteins. On this report, we describe an aptamer-induced, protein-specific bioorthogonal modification expertise for exact non-genetic immobilization of a number of small practical molecules heading in the right direction membrane glycoproteins by combining metabolic expertise and aptamer focusing on.

In briefly, DNA probes had been designed by modifying aptamers, which bind to focus on proteins on the surfaces of dwelling cells pretreated with N-azidoacetylmannosamine-tetraacylated (Ac4ManNAz). The cyclooctynes tagged of DNA probes will strategy the azide teams to set off the bioorthogonal reactions.

After UV irradiation and hybridization with cDNA (complementary DNA), the aptamers will be eliminated, and the method will be repeated to attain a number of modifications for multicolor imaging and cell floor nano-engineering on particular proteins.

 

T0070907

2095-5 each
EUR 216

T0901317

A2249-100 100 mg
EUR 296.4
Description: T0901317 is an agonist for multiple targets, which possesses EC50 values of 20 nM and 5 ?M for LXR? and FXR, respectively. Furthermore, it is ROR? and ROR? dual inverse agonist with estimated IC50 of 2.0 ?M and 1.7 ?M, respectively.

T0901317

A2249-25 25 mg
EUR 142.8
Description: T0901317 is an agonist for multiple targets, which possesses EC50 values of 20 nM and 5 ?M for LXR? and FXR, respectively. Furthermore, it is ROR? and ROR? dual inverse agonist with estimated IC50 of 2.0 ?M and 1.7 ?M, respectively.

T0901317

A2249-5.1 10 mM (in 1mL DMSO)
EUR 142.8
Description: T0901317 is an agonist for multiple targets, which possesses EC50 values of 20 nM and 5 ?M for LXR? and FXR, respectively. Furthermore, it is ROR? and ROR? dual inverse agonist with estimated IC50 of 2.0 ?M and 1.7 ?M, respectively.

T0070907

A4301-10 10 mg
EUR 129.6
Description: T0070907 is a selective antagonist of peroxisome proliferator-activated receptor ? (PPAR?) with IC50 value of 1nM [1].T0070907 shows high affinity to PPAR? with Ki of 1nM.

T0070907

A4301-25 25 mg
EUR 226.8
Description: T0070907 is a selective antagonist of peroxisome proliferator-activated receptor ? (PPAR?) with IC50 value of 1nM [1].T0070907 shows high affinity to PPAR? with Ki of 1nM.

T0070907

A4301-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: T0070907 is a selective antagonist of peroxisome proliferator-activated receptor ? (PPAR?) with IC50 value of 1nM [1].T0070907 shows high affinity to PPAR? with Ki of 1nM.

T0070907

A4301-50 50 mg
EUR 324
Description: T0070907 is a selective antagonist of peroxisome proliferator-activated receptor ? (PPAR?) with IC50 value of 1nM [1].T0070907 shows high affinity to PPAR? with Ki of 1nM.

T0901317

HY-10626 100mg
EUR 325.2

T6167923

HY-19744 5mg
EUR 831.6

T0070907

HY-13202 10mM/1mL
EUR 135.6

T0901317

GL6126-10 10
EUR 74.7

T0901317

GL6126-50 50
EUR 169

JNK1 / 2 / 3 p(T183 / T183 / T221) Antibody

20-abx124933
  • EUR 710.40
  • EUR 1028.40
  • EUR 493.20
  • 100 ul
  • 200 ul
  • 50 ul

Phospho-JNK1/2/3-T183/T183/T221 Rabbit mAb

AP0631 20 μL
EUR 18

Phospho-JNK1/2/3-T183/T183/T221 Rabbit mAb

AP0631-100ul 100 ul
EUR 550.8

Phospho-JNK1/2/3-T183/T183/T221 Rabbit mAb

AP0631-200ul 200 ul
EUR 823.2

Phospho-JNK1/2/3-T183/T183/T221 Rabbit mAb

AP0631-20ul 20 ul
EUR 265.2

Phospho-JNK1/2/3-T183/T183/T221 Rabbit mAb

AP0631-50ul 50 ul
EUR 369.6

Phospho-JNK1/2/3 (T183+T183+T221)

E8ET1609-42 100ul
EUR 275
Description: Available in various conjugation types.

ERK1 / 2 (pT202+T204 / T185+T187) Antibody

abx216707-100ug 100 ug
EUR 526.8

T-3775440 hydrochloride

HY-103085 100mg
EUR 4605.6

Phospho-JNK1/2/3 (T183+T183+T221) Rabbit pAb

E2381100 100ul
EUR 225
Description: Available in various conjugation types.

T-00127_HEV1

HY-108313 1mg
EUR 224.4

In-situ adapter for use with T5000-96

T5000-A-IS 1 PC
EUR 570.1

Anti-Phospho-JNK1/2/3(T183+T183+T221) Antibody [ST500]

ET1609-42 100ul
EUR 231
Description: JNKs (c-Jun N-terminal kinases) belong to a family of MAP kinases that are involved in a variety of cellular processes, including transcriptional regulation and cellular proliferation, differentiation and development. JNK2 (c-Jun N-terminal kinase 2) and JNK3 (c-Jun N-terminal kinase 3) are 424 and 464 amino acid proteins, respectively, that each contain one protein kinase domain and use magnesium as a cofactor to catalyze the phosphorylation of target proteins, thereby playing a role in a variety of events throughout the cell. Both JNK2 and JNK3 exist as multiple alternatively spliced isoforms and are subject to post-translational phosphorylation on Thr 183 and Thr 221, respectively, an event which activates JNK2/JNK3 enzymatic activity. Defects in the gene encoding JNK3 are a cause of epileptic encephalopathy of the Lennox-Gastaut type, a group of epileptic disorders characterized by severe psychomotor delay and seizures.

Anti-Phospho-JNK1/2/3(T183+T183+T221) Antibody [ST500]

ET1609-42TR 20ul
EUR 64.35
Description: JNKs (c-Jun N-terminal kinases) belong to a family of MAP kinases that are involved in a variety of cellular processes, including transcriptional regulation and cellular proliferation, differentiation and development. JNK2 (c-Jun N-terminal kinase 2) and JNK3 (c-Jun N-terminal kinase 3) are 424 and 464 amino acid proteins, respectively, that each contain one protein kinase domain and use magnesium as a cofactor to catalyze the phosphorylation of target proteins, thereby playing a role in a variety of events throughout the cell. Both JNK2 and JNK3 exist as multiple alternatively spliced isoforms and are subject to post-translational phosphorylation on Thr 183 and Thr 221, respectively, an event which activates JNK2/JNK3 enzymatic activity. Defects in the gene encoding JNK3 are a cause of epileptic encephalopathy of the Lennox-Gastaut type, a group of epileptic disorders characterized by severe psychomotor delay and seizures.

T-5224

B4664-10 10 mg
EUR 268.8
Description: T-5224 is a non-peptidic, small molecule and novel inhibitor of c-Fos/AP-1 [1].T-5224 has shown the specific inhibition in a c-Fos/AP-1promoter-luciferase assay, without affecting the levels of c-Fos family protein members themselves.

T-5224

B4664-100 100 mg
EUR 1104
Description: T-5224 is a non-peptidic, small molecule and novel inhibitor of c-Fos/AP-1 [1].T-5224 has shown the specific inhibition in a c-Fos/AP-1promoter-luciferase assay, without affecting the levels of c-Fos family protein members themselves.

T-5224

B4664-5 5 mg
EUR 199.2
Description: T-5224 is a non-peptidic, small molecule and novel inhibitor of c-Fos/AP-1 [1].T-5224 has shown the specific inhibition in a c-Fos/AP-1promoter-luciferase assay, without affecting the levels of c-Fos family protein members themselves.

T-5224

B4664-5.1 10 mM (in 1mL DMSO)
EUR 212.4
Description: T-5224 is a non-peptidic, small molecule and novel inhibitor of c-Fos/AP-1 [1].T-5224 has shown the specific inhibition in a c-Fos/AP-1promoter-luciferase assay, without affecting the levels of c-Fos family protein members themselves.

T-5224

B4664-50 50 mg
EUR 686.4
Description: T-5224 is a non-peptidic, small molecule and novel inhibitor of c-Fos/AP-1 [1].T-5224 has shown the specific inhibition in a c-Fos/AP-1promoter-luciferase assay, without affecting the levels of c-Fos family protein members themselves.

T-5224

9546-25 each
EUR 823.2

T-5224

9546-5 each
EUR 261.6

T-1105

HY-W015764 10mM/1mL
EUR 135.6

T-5224

HY-12270 100mg
EUR 1282.8

T-1105

C6663-100 100mg
EUR 50

T-1105

C6663-200 200mg
EUR 80

In-situ adapter (4 slides) for use with T5000-96

MOL2018 EACH
EUR 746.4

OR2T8 / 2T12 / 2T33 Antibody

20-abx147607
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

OR2T8/2T12/2T33 Antibody

44979-100ul 100ul
EUR 302.4

OR2T8/2T12/2T33 Antibody

44979-50ul 50ul
EUR 224.4

OR2T8/2T12/2T33 Antibody

ABD2825 100 ug
EUR 525.6

OR2T8/2T12/2T33 Antibody

DF2825 100ul
EUR 280
Description: Human,Rat

OR2T8/2T12/2T33 Antibody

DF2825-100ul 100ul
EUR 280

OR2T8/2T12/2T33 Antibody

DF2825-200ul 200ul
EUR 350

Anti-Phospho-JNK1/2/3 (T183+T183+T221) Monoclonal Antibody

MP02608 100ug
EUR 476.4
Description: Rabbit Monoclonal Phospho-JNK1/2/3 (T183+T183+T221) Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-Phospho-MAPK8/MAPK9/MAPK10-(T183/T183/T221) antibody

STJ113512 100 µl
EUR 548.4

Phospho-LATS1/LATS2 (T1079/1041) Antibody

1-CSB-PA070231
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-LATS1/LATS2 (T1079/1041). Recognizes Phospho-LATS1/LATS2 (T1079/1041) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/20000

PTEN (pS380 / T382 / T383) Antibody

20-abx000193
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

PTEN (pS380/T382/T383) Antibody

E38PA4954 100ul
EUR 225
Description: Available in various conjugation types.

Anti-Phospho-LATS1/2 (T1079/1041) antibody

STJ91207 200 µl
EUR 236.4
Description: Rabbit polyclonal to Phospho-LATS1/2 (T1079/1041).

Phospho-Erk1 (T202) +Erk2 (T185)

E8ET1603-22 100ul
EUR 275
Description: Available in various conjugation types.

OR2T8/2T12/2T33 Blocking Peptide

DF2825-BP 1mg
EUR 234

Screw GB/T9074.4 M3x6 2ea

MIX1360 PK2
EUR 8.4

JNK1/2/3(Phospho-T183+T183+T221) Antibody

13371-100ul 100ul
EUR 399.6

JNK1/2/3(Phospho-T183+T183+T221) Antibody

13371-50ul 50ul
EUR 286.8

OR2T8/2T12/2T33 Conjugated Antibody

C44979 100ul
EUR 476.4

Phospho-PTEN (S380/T382/T383) Antibody

1-CSB-PA040052
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-PTEN (S380/T382/T383). Recognizes Phospho-PTEN (S380/T382/T383) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

Screw GB/T9074.4 M5X10 6ea

MIX1362 PK6
EUR 8.4

Phospho-Erk1 (T202/Y204) +Erk2 (T185/Y187)

E8ET1610-13 100ul
EUR 275
Description: Available in various conjugation types.

Phospho-PTEN-S380/T382/T383 Rabbit pAb

AP0141-100ul 100 ul
EUR 460.8

Phospho-PTEN-S380/T382/T383 Rabbit pAb

AP0141-200ul 200 ul
EUR 664.8

Phospho-PTEN-S380/T382/T383 Rabbit pAb

AP0141-20ul 20 ul Ask for price

Phospho-PTEN-S380/T382/T383 Rabbit pAb

AP0141-50ul 50 ul
EUR 318

AMPKα1/2 (T174/T172) polyclonal antibody

E43P0569 100ul
EUR 225
Description: Available in various conjugation types.

Phospho-PTEN-S380/T382/T383 Rabbit mAb

AP1346 200μL
EUR 2340
Description: This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane. This longer isoform may help regulate energy metabolism in the mitochondria. A pseudogene of this gene is found on chromosome 9. Alternative splicing and the use of multiple translation start codons results in multiple transcript variants encoding different isoforms.

Phospho-ERK1 (T202) + ERK2 (T185) Rabbit pAb

E2382155 100ul
EUR 225
Description: Available in various conjugation types.

Tocrifluor T1117

B7096-.1 100 ug
EUR 614.4

Rabbit anti-PTEN (pS380/T382/T383) Antibody

YLD6506-100ul 100 ul
EUR 320
Description: Rabbit polyclonal antibody to PTEN (pS380/T382/T383)

Rabbit anti-PTEN (pS380/T382/T383) Antibody

YLD6506-50ul 50 ul
EUR 200
Description: Rabbit polyclonal antibody to PTEN (pS380/T382/T383)

Rabbit anti-PTEN (pS380/T382/T383) Antibody

DL93954A-100ul 100 ul
EUR 370
Description: MMAC1; TEP1; Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog

Rabbit anti-PTEN (pS380/T382/T383) Antibody

DL93954A-50ul 50 ul
EUR 259
Description: MMAC1; TEP1; Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog

Phospho-PAK1/PAK2/PAK3 (T423/402/421) Antibody

1-CSB-PA020212
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-PAK1/PAK2/PAK3 (T423/402/421). Recognizes Phospho-PAK1/PAK2/PAK3 (T423/402/421) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000

Polyclonal PTEN Antibody (Center T383/T382)

AMR09600G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PTEN (Center T383/T382). This antibody is tested and proven to work in the following applications:

CD45RO(T200/797) Antibody

BNC800797-100 100uL
EUR 238.8
Description: Primary antibody against CD45RO(T200/797), CF680 conjugate, Concentration: 0.1mg/mL

CD45RO(T200/797) Antibody

BNC800797-500 500uL
EUR 652.8
Description: Primary antibody against CD45RO(T200/797), CF680 conjugate, Concentration: 0.1mg/mL

CD45RO(T200/797) Antibody

BNC810797-100 100uL
EUR 238.8
Description: Primary antibody against CD45RO(T200/797), CF680R conjugate, Concentration: 0.1mg/mL

CD45RO(T200/797) Antibody

BNC810797-500 500uL
EUR 652.8
Description: Primary antibody against CD45RO(T200/797), CF680R conjugate, Concentration: 0.1mg/mL

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