Rat Retinoblastoma-Like Protein ELISA Kit

 

Phosphorylated retinoblastoma protein (p-Rb) is concerned in neuronal apoptosis after traumatic mind damage in grownup rats.

 

Phosphorylated retinoblastoma protein (p-Rb), a effectively recognized cell cycle associated protein, is concerned in regulating the organic features of assorted cell varieties together with neurons. One enticing biological operate of p-Rb is releasing E2F transcription issue to induce S-phase entry and mobile proliferation of mitotic cells.

 

Mouse Retinoblastoma-Like Protein 2 (RBL2) ELISA Equipment

Nonetheless, some research level out that the position of p-Rb in post-mitotic cells akin to mature neurons is exclusive; it might induce mobile apoptosis somewhat than proliferation through regulating cell cycle reactivation. Thus far, the data of p-Rb operate in CNS continues to be restricted. To research whether or not p-Rb is concerned in CNS damage and restore, we carried out a traumatic mind damage mannequin in grownup rats.

 

 

 

Up-regulation of p-Rb was noticed within the injured mind cortex by western blot evaluation and immunohistochemistry staining. Terminal deoxynucleotidyl transferase deoxy-UTP-nick finish labeling (TUNEL) and 4′,6-diamidino-2-phenylindole (DAPI) staining recommended that p-Rb was related to neuronal apoptosis after mind damage. As well as, glutamate excitotoxic mannequin of main cortex neurons was launched to additional examine the position of p-Rb in neuronal apoptosis; the consequence implied p-Rb was related to cell cycle activation within the apoptotic neurons.

Monkey Retinoblastoma Protein 1 ELISA equipment

A sandwich ELISA for quantitative measurement of Monkey Retinoblastoma Protein 1 in samples from blood, plasma, serum, cell tradition supernatant and different organic fluids. It is a prime quality ELISA equipment developped for optimum efficiency with samples from the actual species.

 

Primarily based on our information, we recommended that p-Rb may play an essential position in neuronal apoptosis after traumatic mind damage in rat; which could additionally present a foundation for the additional study on its position in regulating cell cycle re-entry in apoptotic neurons, and may acquire a novel technique for the medical remedy for traumatic mind damage.

 

 

HRP-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052554-05mL 0.5mL
EUR 430

HRP-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052554-1mL 1mL
EUR 520

HRP-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052554-5mL 5mL
EUR 1450

HRP-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052555-01mL 0.1mL
EUR 195

HRP-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052555-02mL 0.2mL
EUR 245

HRP-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052555-05mL 0.5mL
EUR 430

HRP-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052555-1mL 1mL
EUR 520

HRP-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052555-5mL 5mL
EUR 1450

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

PAB211Hu01 100ul
EUR 232

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

PAB211Hu02 100ul
EUR 232

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005835-01mL 0.1mL
EUR 170

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005835-02mL 0.2mL
EUR 205

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005835-05mL 0.5mL
EUR 335

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005835-1mL 1mL
EUR 415

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005835-5mL 5mL
EUR 1130

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005550-01mL 0.1mL
EUR 170

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005550-02mL 0.2mL
EUR 205

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005550-05mL 0.5mL
EUR 335

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005550-1mL 1mL
EUR 415

Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2005550-5mL 5mL
EUR 1130

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), HRP

4-PAB211Hu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with HRP.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), HRP

4-PAB211Hu02-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with HRP.

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052546-01mL 0.1mL
EUR 260

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052546-02mL 0.2mL
EUR 335

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052546-05mL 0.5mL
EUR 630

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052546-1mL 1mL
EUR 770

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052546-5mL 5mL
EUR 2210

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052547-01mL 0.1mL
EUR 260

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052547-02mL 0.2mL
EUR 335

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052547-05mL 0.5mL
EUR 630

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052547-1mL 1mL
EUR 770

PE-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052547-5mL 5mL
EUR 2210

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052548-01mL 0.1mL
EUR 260

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052548-02mL 0.2mL
EUR 335

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052548-05mL 0.5mL
EUR 630

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052548-1mL 1mL
EUR 770

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052548-5mL 5mL
EUR 2210

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052549-01mL 0.1mL
EUR 260

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052549-02mL 0.2mL
EUR 335

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052549-05mL 0.5mL
EUR 630

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052549-1mL 1mL
EUR 770

APC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052549-5mL 5mL
EUR 2210

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052550-01mL 0.1mL
EUR 260

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052550-02mL 0.2mL
EUR 335

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052550-05mL 0.5mL
EUR 630

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052550-1mL 1mL
EUR 770

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052550-5mL 5mL
EUR 2210

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052551-01mL 0.1mL
EUR 260

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052551-02mL 0.2mL
EUR 335

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052551-05mL 0.5mL
EUR 630

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052551-1mL 1mL
EUR 770

Cy3-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052551-5mL 5mL
EUR 2210

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052552-01mL 0.1mL
EUR 205

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052552-02mL 0.2mL
EUR 260

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052552-05mL 0.5mL
EUR 460

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052552-1mL 1mL
EUR 555

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052552-5mL 5mL
EUR 1560

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052553-01mL 0.1mL
EUR 205

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052553-02mL 0.2mL
EUR 260

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052553-05mL 0.5mL
EUR 460

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052553-1mL 1mL
EUR 555

FITC-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052553-5mL 5mL
EUR 1560

Biotin-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2092996-01mL 0.1mL
EUR 175

Biotin-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2092996-02mL 0.2mL
EUR 225

Biotin-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2092996-05mL 0.5mL
EUR 370

Biotin-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2092996-1mL 1mL
EUR 450

Biotin-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2092996-5mL 5mL
EUR 1235

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody

CAU26358-100ul 100ul
EUR 222.7

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody

CAU26358-200ul 200ul
EUR 278.9

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody

CAU26359-100ul 100ul
EUR 222.7

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody

CAU26359-200ul 200ul
EUR 278.9

APC/CY7-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052544-1mL 1mL
EUR 1130

APC/CY7-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052544-5mL 5mL
EUR 3270

APC/CY7-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052544-5x5mL 5x5mL
EUR 14705

APC/CY7-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052545-1mL 1mL
EUR 1130

APC/CY7-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052545-5mL 5mL
EUR 3270

APC/CY7-Linked Polyclonal Antibody to Retinoblastoma Protein 1 (RB1)

MBS2052545-5x5mL 5x5mL
EUR 14705

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human)

4-PAB211Hu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1)

 

Treating retinoblastoma in tissue tradition and in a rat mannequin with a novel isoquinoline by-product.

 

  • PURPOSE. To research the effectiveness of a novel isoquinoline by-product, EDL-155, in killing retinoblastoma in vitro and in vivo. METHODS. Dose-response curves have been generated during which Y79 retinoblastoma cells tagged with luciferase (Y79-Luc) have been handled with serial concentrations of EDL-155.

 

  • Electron microscopy was used to judge the ultrastructural morphology of EDL-155-treated Y79 cells. To find out whether or not autophagy was induced in EDL-155-treated Y79-Luc cells, staining with acridine orange and LC-Three immunoblot evaluation was carried out.

Guinea pig Retinoblastoma Protein 1 ELISA equipment

  A sandwich ELISA for quantitative measurement of Guinea pig Retinoblastoma Protein 1 in samples from blood, plasma, serum, cell tradition supernatant and different organic fluids. It is a prime quality ELISA equipment developped for optimum efficiency with samples from the actual species.

  • To guage the efficacy of EDL-155 in vivo, Y79-Luc retinoblastoma cells have been injected into the vitreous cavity of new child rats, adopted by periocular injections of EDL-155 (20 mg/kg/day) or an equal dosage of saline.

 

  • RESULTS. EDL-155 appeared to destroy the retinoblastoma cells in vitro with an EC(50) of 9.1 micriM. EDL-155-treated retinoblastoma cells displayed a scarcity of viable mitochondria and the presence of autophagosomes wrapped within the attribute double membranes.

Rat Retinoblastoma Like, RBL1 GENLISA ELISA

KLR1580 1 x 96 wells
EUR 341

Rat Retinoblastoma-like,RBL1 ELISA KIT

E1580Ra-1096T 10*96T
EUR 4122

Rat Retinoblastoma-like,RBL1 ELISA KIT

E1580Ra-48wells 48 wells
EUR 300

Rat Retinoblastoma-like,RBL1 ELISA KIT

E1580Ra-596T 5*96T
EUR 2061

Rat Retinoblastoma-like,RBL1 ELISA KIT

E1580Ra-96wells 96 wells
EUR 458

Rat Retinoblastoma-like (RBL1) ELISA Kit

MBS1600573-10x96StripWells 10x96-Strip-Wells
EUR 3955

Rat Retinoblastoma-like (RBL1) ELISA Kit

MBS1600573-48StripWells 48-Strip-Wells
EUR 305

Rat Retinoblastoma-like (RBL1) ELISA Kit

MBS1600573-5x96StripWells 5x96-Strip-Wells
EUR 2005

Rat Retinoblastoma-like (RBL1) ELISA Kit

MBS1600573-96StripWells 96-Strip-Wells
EUR 475

Cat Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9345904-INQUIRE INQUIRE Ask for price

Fish Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9362288-INQUIRE INQUIRE Ask for price

Duck Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9358130-INQUIRE INQUIRE Ask for price

Goat Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9358592-INQUIRE INQUIRE Ask for price

Cavy Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9354022-INQUIRE INQUIRE Ask for price

Human Retinoblastoma-like protein 1 (RBL1) ELISA Kit

abx250655-96tests 96 tests
EUR 801.6

Mouse Retinoblastoma-like protein 1 (RBL1) ELISA Kit

abx515799-96tests 96 tests
EUR 801.6

Human Retinoblastoma-like protein 1 (RBL1) Elisa Kit

EK716119 96 Wells
EUR 0.52

Mouse Retinoblastoma-like protein 1 (RBL1) ELISA Kit

AE22775MO-48T 48T
EUR 325
Description: Mouse (Mus musculus)

Mouse Retinoblastoma-like protein 1 (RBL1) ELISA Kit

AE22775MO-96T 96T
EUR 610
Description: Mouse (Mus musculus)

Human Retinoblastoma-like protein 1 (RBL1) ELISA Kit

AE22776HU-48T 48T
EUR 360
Description: Human (Homo sapiens)

Human Retinoblastoma-like protein 1 (RBL1) ELISA Kit

AE22776HU-96T 96T
EUR 610
Description: Human (Homo sapiens)

Human Retinoblastoma-like protein 1 (RBL1) ELISA Kit

RK07854 96T
EUR 280

Mouse Retinoblastoma-like protein 1 (RBL1) ELISA Kit

RK07855 96T
EUR 280

Goose Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9363580-INQUIRE INQUIRE Ask for price

Camel Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9343814-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9343814-48StripWells 48-Strip-Wells
EUR 550

Camel Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9343814-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9343814-96StripWells 96-Strip-Wells
EUR 765

Horse Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9348804-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9348804-48StripWells 48-Strip-Wells
EUR 550

Horse Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9348804-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9348804-96StripWells 96-Strip-Wells
EUR 765

Mouse Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9352873-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9352873-48StripWells 48-Strip-Wells
EUR 550

Mouse Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9352873-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9352873-96StripWells 96-Strip-Wells
EUR 765

Human Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9353502-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9353502-48StripWells 48-Strip-Wells
EUR 550

Human Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9353502-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9353502-96StripWells 96-Strip-Wells
EUR 765

Mouse Retinoblastoma-like protein 1, RBL1 ELISA Kit

MBS9319848-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Retinoblastoma-like protein 1, RBL1 ELISA Kit

MBS9319848-48StripWells 48-Strip-Wells
EUR 550

Mouse Retinoblastoma-like protein 1, RBL1 ELISA Kit

MBS9319848-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Retinoblastoma-like protein 1, RBL1 ELISA Kit

MBS9319848-96StripWells 96-Strip-Wells
EUR 765

Human Retinoblastoma-like protein 1, RBL1 ELISA Kit

MBS9320053-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Retinoblastoma-like protein 1, RBL1 ELISA Kit

MBS9320053-48StripWells 48-Strip-Wells
EUR 550

Human Retinoblastoma-like protein 1, RBL1 ELISA Kit

MBS9320053-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Retinoblastoma-like protein 1, RBL1 ELISA Kit

MBS9320053-96StripWells 96-Strip-Wells
EUR 765

Plant Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9372686-INQUIRE INQUIRE Ask for price

Sheep Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9345310-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9345310-48StripWells 48-Strip-Wells
EUR 550

Sheep Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9345310-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9345310-96StripWells 96-Strip-Wells
EUR 765

Bovine Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9347297-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9347297-48StripWells 48-Strip-Wells
EUR 550

Bovine Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9347297-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9347297-96StripWells 96-Strip-Wells
EUR 765

Donkey Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9347815-INQUIRE INQUIRE Ask for price

Rabbit Retinoblastoma-Like Protein 1 (RBL1) ELISA Kit

MBS9348066-INQUIRE INQUIRE Ask for price
  • Acridine orange staining of EDL-155-treated retinoblastoma cells demonstrated the buildup of vacuoles, and the immunoblots displayed a shift in molecular weight of LC-3, indicative of incorporation into autophagosome vesicles.

 

  • Within the retinoblastoma animal mannequin, 4 doses of EDL-155 have been delivered over Four days, which was ample to see a major lower (P = 0.01) in viable intraocular tumors.

Human RB1(Retinoblastoma Protein 1) ELISA Equipment

  • Seven of the 25 rats handled with EDL-155 had no detectable dwelling tumor. No important lower in viable tumor was noticed in management animals. CONCLUSIONS. EDL-155 seems to remove retinoblastoma cells by disrupting mitochondria and inducing autophagy. Native supply of EDL-155 could also be an efficient remedy for some kinds of ocular cancers.