Rat Retinoblastoma-Like Protein ELISA Kit

 

Phosphorylated retinoblastoma protein (p-Rb) is concerned in neuronal apoptosis after traumatic mind damage in grownup rats.

 

Phosphorylated retinoblastoma protein (p-Rb), a effectively recognized cell cycle associated protein, is concerned in regulating the organic features of assorted cell varieties together with neurons. One enticing biological operate of p-Rb is releasing E2F transcription issue to induce S-phase entry and mobile proliferation of mitotic cells.

 

Mouse Retinoblastoma-Like Protein 2 (RBL2) ELISA Equipment

Nonetheless, some research level out that the position of p-Rb in post-mitotic cells akin to mature neurons is exclusive; it might induce mobile apoptosis somewhat than proliferation through regulating cell cycle reactivation. Thus far, the data of p-Rb operate in CNS continues to be restricted. To research whether or not p-Rb is concerned in CNS damage and restore, we carried out a traumatic mind damage mannequin in grownup rats.

 

 

 

Up-regulation of p-Rb was noticed within the injured mind cortex by western blot evaluation and immunohistochemistry staining. Terminal deoxynucleotidyl transferase deoxy-UTP-nick finish labeling (TUNEL) and 4′,6-diamidino-2-phenylindole (DAPI) staining recommended that p-Rb was related to neuronal apoptosis after mind damage. As well as, glutamate excitotoxic mannequin of main cortex neurons was launched to additional examine the position of p-Rb in neuronal apoptosis; the consequence implied p-Rb was related to cell cycle activation within the apoptotic neurons.

Monkey Retinoblastoma Protein 1 ELISA equipment

A sandwich ELISA for quantitative measurement of Monkey Retinoblastoma Protein 1 in samples from blood, plasma, serum, cell tradition supernatant and different organic fluids. It is a prime quality ELISA equipment developped for optimum efficiency with samples from the actual species.

 

Primarily based on our information, we recommended that p-Rb may play an essential position in neuronal apoptosis after traumatic mind damage in rat; which could additionally present a foundation for the additional study on its position in regulating cell cycle re-entry in apoptotic neurons, and may acquire a novel technique for the medical remedy for traumatic mind damage.

 

 

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), HRP

4-PAB211Hu01-HRP
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with HRP.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), HRP

4-PAB211Hu02-HRP
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  • 100ul
  • 10ml
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with HRP.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody

CAU26358-100ul 100ul
EUR 222.7

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody

CAU26358-200ul 200ul
EUR 278.9

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody

CAU26359-100ul 100ul
EUR 222.7

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody

CAU26359-200ul 200ul
EUR 278.9

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human)

4-PAB211Hu01
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  • 100ul
  • 10ml
  • 1ml
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1)

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human)

4-PAB211Hu02
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  • 100ul
  • 10ml
  • 1ml
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1)

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), PE

4-PAB211Hu01-PE
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with PE.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), PE

4-PAB211Hu02-PE
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with PE.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), APC

4-PAB211Hu01-APC
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  • 100ul
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  • 1ml
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with APC.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), Cy3

4-PAB211Hu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with Cy3.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), APC

4-PAB211Hu02-APC
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with APC.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), Cy3

4-PAB211Hu02-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with Cy3.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), FITC

4-PAB211Hu01-FITC
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  • 100ul
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  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with FITC.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), FITC

4-PAB211Hu02-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with FITC.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), APC-Cy7

4-PAB211Hu01-APC-Cy7
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with APC-Cy7.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), APC-Cy7

4-PAB211Hu02-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with APC-Cy7.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), Biotinylated

4-PAB211Hu01-Biotin
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with Biotin.

Retinoblastoma Protein 1 (RB1) Polyclonal Antibody (Human), Biotinylated

4-PAB211Hu02-Biotin
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human Retinoblastoma Protein 1 (RB1). This antibody is labeled with Biotin.

Retinoblastoma Protein 1 (RB1) Antibody

20-abx102399
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  • 100 ug
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  • 1 mg
  • 200 ug
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx102401
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  • 100 ug
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  • 1 mg
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx121694
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  • 100 ul
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  • 30 ul

Retinoblastoma Protein 1 (RB1) Antibody

20-abx123188
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  • 100 ul
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  • 20 ul
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx126458
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  • 100 ul
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx141027
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  • 100 ul
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx141070
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  • 100 ul
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx141167
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  • 100 ul
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx136094
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  • 100 ul
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Retinoblastoma Protein 1 (RB1) Antibody

abx037361-100ug 100 ug
EUR 469.2

Retinoblastoma Protein 1 (RB1) Antibody

abx034004-400ul 400 ul
EUR 627.6

Retinoblastoma Protein 1 (RB1) Antibody

abx034004-80l 80 µl
EUR 343.2

Retinoblastoma Protein 1 (RB1) Antibody

abx032759-400ul 400 ul
EUR 627.6

Retinoblastoma Protein 1 (RB1) Antibody

abx032759-80l 80 µl
EUR 343.2

Retinoblastoma Protein 1 (RB1) Antibody

abx011911-100ul 100 ul
EUR 493.2

Retinoblastoma Protein 1 (RB1) Antibody

20-abx008782
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx001728
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  • 100 ul
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Retinoblastoma Protein 1 (RB1) Antibody

20-abx214314
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  • 100 ul
  • 50 ul

Retinoblastoma Protein 1 (RB1) Antibody

abx332050-100ul 100 ul
EUR 510

Retinoblastoma Protein 1 (RB1) Antibody

abx332098-100ul 100 ul
EUR 510

Retinoblastoma Protein 1 (RB1) Antibody

abx332214-100ul 100 ul
EUR 510

Retinoblastoma Protein 1 (RB1) Antibody

20-abx326789
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  • 100 ug
  • 50 ug

Retinoblastoma Protein 1 (RB1) Antibody

20-abx326790
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  • 100 ug
  • 50 ug

Retinoblastoma Protein 1 (RB1) Antibody

20-abx326791
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  • 100 ug
  • 50 ug

Retinoblastoma Protein 1 (RB1) Antibody

20-abx328550
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  • 100 ug
  • 50 ug

Retinoblastoma Protein 1 (RB1) Antibody

20-abx328752
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  • 100 ug
  • 50 ug

Retinoblastoma Protein 1 (RB1) Antibody

20-abx329342
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  • 100 ug
  • 50 ug

Retinoblastoma Protein 1 (RB1) Antibody

20-abx329620
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  • 100 ug
  • 50 ug

Retinoblastoma Protein 1 (RB1) Antibody

abx331681-100ul 100 ul
EUR 510

Retinoblastoma Protein 1 (RB1) Antibody

abx237141-100ug 100 ug
EUR 610.8

Retinoblastoma Protein 1 (RB1) Antibody

abx237142-100ug 100 ug
EUR 661.2

Retinoblastoma Protein 1 (RB1) Antibody

20-abx320518
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  • 100 ul
  • 50 ul

Retinoblastoma Protein 1 (RB1) Antibody

abx011911-100g 100 µg Ask for price

Retinoblastoma Protein 1 (RB1) Antibody

abx011911-10g 10 µg
EUR 362.5

Retinoblastoma Protein 1 (RB1) Antibody

abx011911-200g 200 µg Ask for price

Retinoblastoma Protein 1 (RB1) Antibody

abx102399-100l 100 µl
EUR 262.5

Retinoblastoma Protein 1 (RB1) Antibody

abx102399-1ml 1 ml
EUR 712.5

Retinoblastoma Protein 1 (RB1) Antibody

abx102399-200l 200 µl
EUR 325

Retinoblastoma Protein 1 (RB1) Antibody

abx102401-100l 100 µl
EUR 262.5

Retinoblastoma Protein 1 (RB1) Antibody

abx102401-1ml 1 ml
EUR 712.5

Retinoblastoma Protein 1 (RB1) Antibody

abx102401-200l 200 µl
EUR 325

Retinoblastoma Protein 1 (RB1) Antibody

abx126458-100l 100 µl
EUR 175

Retinoblastoma Protein 1 (RB1) Antibody

abx126458-1ml 1 ml
EUR 400

Retinoblastoma Protein 1 (RB1) Antibody

abx126458-200l 200 µl
EUR 275

Retinoblastoma Protein 1 (RB1) Antibody

abx214314-100g 100 µg
EUR 350

Retinoblastoma Protein 1 (RB1) Antibody

abx214314-25g 25 µg
EUR 250

Retinoblastoma Protein 1 (RB1) Antibody

abx123188-100l 100 µl
EUR 200

Retinoblastoma Protein 1 (RB1) Antibody

abx123188-1ml 1 ml
EUR 475

Retinoblastoma Protein 1 (RB1) Antibody

abx123188-200l 200 µl
EUR 325

Retinoblastoma Protein 1 (RB1) Antibody

abx037361-1096tests 10 × 96 tests Ask for price

Retinoblastoma Protein 1 (RB1) Antibody

abx037361-596tests 5 × 96 tests Ask for price

Retinoblastoma Protein 1 (RB1) Antibody

abx037361-96tests 96 tests
EUR 337.5

Retinoblastoma Protein 1 (RB1) Antibody

abx032759-400l 400 µl
EUR 518.75

Retinoblastoma Protein 1 (RB1) Antibody

abx034004-100g 100 µg
EUR 281.25

Retinoblastoma Protein 1 (RB1) Antibody

abx237140-100g 100 µg
EUR 350

Retinoblastoma Protein 1 (RB1) Antibody

abx237141-100g 100 µg
EUR 350

Retinoblastoma Protein 1 (RB1) Antibody

abx237142-100g 100 µg
EUR 350

Retinoblastoma Protein 1 (RB1) Antibody

abx326789-100g 100 µg
EUR 250

 

Treating retinoblastoma in tissue tradition and in a rat mannequin with a novel isoquinoline by-product.

 

  • PURPOSE. To research the effectiveness of a novel isoquinoline by-product, EDL-155, in killing retinoblastoma in vitro and in vivo. METHODS. Dose-response curves have been generated during which Y79 retinoblastoma cells tagged with luciferase (Y79-Luc) have been handled with serial concentrations of EDL-155.

 

  • Electron microscopy was used to judge the ultrastructural morphology of EDL-155-treated Y79 cells. To find out whether or not autophagy was induced in EDL-155-treated Y79-Luc cells, staining with acridine orange and LC-Three immunoblot evaluation was carried out.

Guinea pig Retinoblastoma Protein 1 ELISA equipment

  A sandwich ELISA for quantitative measurement of Guinea pig Retinoblastoma Protein 1 in samples from blood, plasma, serum, cell tradition supernatant and different organic fluids. It is a prime quality ELISA equipment developped for optimum efficiency with samples from the actual species.

  • To guage the efficacy of EDL-155 in vivo, Y79-Luc retinoblastoma cells have been injected into the vitreous cavity of new child rats, adopted by periocular injections of EDL-155 (20 mg/kg/day) or an equal dosage of saline.

 

  • RESULTS. EDL-155 appeared to destroy the retinoblastoma cells in vitro with an EC(50) of 9.1 micriM. EDL-155-treated retinoblastoma cells displayed a scarcity of viable mitochondria and the presence of autophagosomes wrapped within the attribute double membranes.

Human Retinoblastoma-like protein 1 (RBL1) ELISA Kit

RK07854 96T
EUR 280

Mouse Retinoblastoma-like protein 1 (RBL1) ELISA Kit

RK07855 96T
EUR 280

Human RBL1(Retinoblastoma-like protein 1) ELISA Kit

EH1382 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human RBL1/ Retinoblastoma-like protein 1 ELISA Kit

E2830Hu 1 Kit
EUR 515
Description: 107 kDa retinoblastoma-associated protein,pRb1,p107

Human RBL1 / Retinoblastoma-like protein 1 ELISA Kit

E1211h 96T
EUR 736

Mouse Rbl1 / Retinoblastoma-like protein 1 ELISA Kit

E1211m 96T
EUR 776

Mouse Retinoblastoma Like 1, RBL1/P107 GENLISA ELISA

KLM1685 1 x 96 wells
EUR 341

Mouse Retinoblastoma- like protein 2, Rbl2 ELISA KIT

ELI-36002m 96 Tests
EUR 1038

Human Retinoblastoma- like protein 2, RBL2 ELISA KIT

ELI-19531h 96 Tests
EUR 988.8

Retinoblastoma-Like Protein 1 (RBL1) Antibody

abx030987-400ul 400 ul
EUR 627.6

Retinoblastoma-Like Protein 1 (RBL1) Antibody

abx030987-80l 80 µl
EUR 343.2

Retinoblastoma-like protein 1 (RBL1) Antibody

20-abx325137
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  • 100 ug
  • 50 ug

Retinoblastoma-Like Protein 1 (RBL1) Antibody

20-abx317949
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  • 100 ug
  • 1 mg
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  • 20 ug
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Retinoblastoma-Like Protein 1 (RBL1) Antibody

abx030987-400l 400 µl
EUR 518.75

Retinoblastoma-like protein 1 (RBL1) Antibody

abx325137-100g 100 µg
EUR 250

Retinoblastoma-like protein 1 (RBL1) Antibody

abx325137-50g 50 µg
EUR 187.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody

abx317949-100g 100 µg
EUR 362.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody

abx317949-20g 20 µg
EUR 162.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody

abx317949-50g 50 µg
EUR 250

Rbl1 (untagged) - Rat retinoblastoma-like 1 (p107) (Rbl1)

RN217437 10 µg Ask for price

Retinoblastoma-Like Protein 1 (RBL1) Antibody (HRP)

20-abx305064
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Retinoblastoma-Like Protein 1 (RBL1) Antibody (HRP)

abx305064-100g 100 µg
EUR 362.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody (HRP)

abx305064-20g 20 µg
EUR 162.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody (HRP)

abx305064-50g 50 µg
EUR 250

Retinoblastoma-Like Protein 1 (RBL1) Antibody (FITC)

20-abx305065
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Retinoblastoma-Like Protein 1 (RBL1) Antibody (FITC)

abx305065-100g 100 µg
EUR 362.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody (FITC)

abx305065-20g 20 µg
EUR 162.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody (FITC)

abx305065-50g 50 µg
EUR 250

Retinoblastoma-Like Protein 1 (RBL1) Antibody (Biotin)

20-abx305066
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Retinoblastoma-Like Protein 1 (RBL1) Antibody (Biotin)

abx305066-100g 100 µg
EUR 362.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody (Biotin)

abx305066-20g 20 µg
EUR 162.5

Retinoblastoma-Like Protein 1 (RBL1) Antibody (Biotin)

abx305066-50g 50 µg
EUR 250

Rat Retinoblastoma-Like Protein 2 (RBL2) ELISA Kit

abx391906-96tests 96 tests
EUR 1093.2

Rat Retinoblastoma-Like Protein 2 (RBL2) ELISA Kit

abx391906-500g 500 µg
EUR 687.5

Rbl2 ELISA Kit| Rat Retinoblastoma-like protein 2 ELISA Kit

EF019266 96 Tests
EUR 826.8

Human Retinoblastoma-Like, RBL1 GENLISA ELISA

KBH4322 1 x 96 wells
EUR 286

Rat Rbl2 / Retinoblastoma-like protein 2 ELISA Kit

E12098r 96T
EUR 796

Rbl1 (myc-DDK-tagged) - Rat retinoblastoma-like 1 (p107) (Rbl1)

RR217437 10 µg Ask for price

Rbl1 (GFP-tagged) - Mouse retinoblastoma-like 1 (p107) (Rbl1)

MG211567 10 µg Ask for price

Mouse Retinoblastoma-Like Protein 2 (RBL2) ELISA Kit

abx390448-96tests 96 tests
EUR 1093.2

Human Retinoblastoma-Like Protein 2 (RBL2) ELISA Kit

abx382711-96tests 96 tests
EUR 1093.2

Mouse Retinoblastoma-like protein 2 (RBL2) ELISA Kit

RK13621 96T
EUR 280

Human Retinoblastoma-like protein 2 (RBL2) ELISA Kit

RK11797 96T
EUR 280

Mouse Retinoblastoma-Like Protein 2 (RBL2) ELISA Kit

abx390448-500g 500 µg
EUR 687.5

Rbl2 ELISA Kit| Mouse Retinoblastoma-like protein 2 ELISA Kit

EF016090 96 Tests
EUR 826.8

Retinoblastoma-like protein 1 Phospho-Thr369 (RBL1 pT369) Antibody

20-abx325278
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  • 100 ug
  • 50 ug

Retinoblastoma-like protein 1 Phospho-Thr369 (RBL1 pT369) Antibody

abx325278-100g 100 µg
EUR 250

Retinoblastoma-like protein 1 Phospho-Thr369 (RBL1 pT369) Antibody

abx325278-50g 50 µg
EUR 187.5

Human RBL2 / Retinoblastoma-like protein 2 ELISA Kit

E12098h 96T
EUR 736

Mouse Rbl2 / Retinoblastoma-like protein 2 ELISA Kit

E12098m 96T
EUR 776

RBL1 (untagged)-Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 1

SC109714 10 µg Ask for price

RBL1 (untagged)-Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 2

SC109715 10 µg Ask for price

RBL1 (GFP-tagged) - Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 1

RG215873 10 µg Ask for price

RBL1 (GFP-tagged) - Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 2

RG207017 10 µg Ask for price

Human Retinoblastoma-like protein 2 (RBL2)

1-CSB-EP600921HU
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  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Retinoblastoma-like protein 2(RBL2),partial expressed in E.coli

Rbl1 (Myc-DDK-tagged) - Mouse retinoblastoma-like 1 (p107) (Rbl1), transcript variant 1

MR211567 10 µg Ask for price

RBL1 (Myc-DDK-tagged)-Human retinoblastoma-like 1 (p107) (RBL1), transcript variant 1

RC215873 10 µg Ask for price

Retinoblastoma-Like Protein 2 (RBL2) Antibody

abx224096-100ug 100 ug
EUR 493.2

Retinoblastoma-Like Protein 2 (RBL2) Antibody

abx224096-100l 100 µl Ask for price
  • Acridine orange staining of EDL-155-treated retinoblastoma cells demonstrated the buildup of vacuoles, and the immunoblots displayed a shift in molecular weight of LC-3, indicative of incorporation into autophagosome vesicles.

 

  • Within the retinoblastoma animal mannequin, 4 doses of EDL-155 have been delivered over Four days, which was ample to see a major lower (P = 0.01) in viable intraocular tumors.

Human RB1(Retinoblastoma Protein 1) ELISA Equipment

  • Seven of the 25 rats handled with EDL-155 had no detectable dwelling tumor. No important lower in viable tumor was noticed in management animals. CONCLUSIONS. EDL-155 seems to remove retinoblastoma cells by disrupting mitochondria and inducing autophagy. Native supply of EDL-155 could also be an efficient remedy for some kinds of ocular cancers.